Just about every week I encounter some malware that is completely protected from deletion no matter what anti-malware application I use, even in safemode. For these annoying files I use Pocket Killbox (from bleepingcomputer). Pocket Killbox can remove any piece of malware, or really any file.
Below are some instructions on how to delete any virus ( malware ) :
How to Delete Any File.
1. Download Pocket KillBox from here to your Desktop.
2. Open Kill Box and you will see the interface below.
3. Click the yellow folder to browse to the file you wish to delete.
4. Make SURE your option match the ones below. Of course your file chosen will be different.
5. Click the red x to delete the file.
6. Reboot.
7. It will look like the file is there still, however this is an empty file now and may be ignored or freely deleted.
