I have heard unfounded rumours that Chrome has its own sandbox. I assume that would be for surfing only, no downloads, otherwise it would be obvious becuase you would have to manually extract what you download out of the virtual realm, just like you do with sandboxie.
When I try to open chrome in Sandboxie, I get a message something like this: "SBIE2102 File is too large to copy into sandbox: Thumbnails"
Windows XP Professional 2002 sp3 32bit
Aggressive AVIRA 10, MBAM, SAS, Sandbox
Everything that has been and everything that will be, exists, in some form, within and without, the known and unknown universe.