As far as I can tell you should NOT use Combofix on Windows Vista and Windows 7.
*EDIT* – As of 2011 Combofix has been very stable on Windows 7
I’ve been doing some pretty extensive testing with Combofix in VMware and my VM’s were corrupted about 50% of the time (unbootable). I’ve really only used Combofix on Windows XP 32-bit to get rid of rootkits quickly and easily. Since more and more PC’s are being shipped with 64-bit OS’s dealing with malware has gotten a lot easier in the past few months for me since Rootkits cannot be installed in a 64-bit OS.




